| 3-NT | 3-nitrotyrosine |
| 4-HNE | 4-hydroxynonenal |
| 8-epi-PGF2α | 8-epi-prostaglandin F2α |
| 8-OHdG | 8-hydroxy-2′-deoxyguanosine |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| AGE/AGEs | advanced glycation end product(s) |
| Akt | protein kinase B |
| ALDH2 | aldehyde dehydrogenase 2 |
| AMI | acute myocardial infarction |
| AMPK | AMP-activated protein kinase |
| ARIC | Atherosclerosis Risk in Communities |
| ATP | adenosine triphosphate |
| BAK | Bcl-2 homologous antagonist/killer |
| BAP | biological antioxidant potential |
| BAX | Bcl-2-associated X protein |
| BIOSTAT-CHF | A Systems BIOlogy Study to TAilored Treatment in Chronic Heart Failure |
| BNP | B-type natriuretic peptide |
| CA-125 | carbohydrate antigen 125 |
| Ca2+ | calcium ion |
| cGAS-STING | cyclic GMP–AMP synthase–stimulator of interferon genes |
| cGMP-PKG | cyclic guanosine monophosphate–protein kinase G |
| CECCY | Carvedilol Effect in Preventing Chemotherapy-Induced Cardiotoxicity |
| CMR | cardiac magnetic resonance |
| COPD | chronic obstructive pulmonary disease |
| CT-1 | cardiotrophin-1 |
| DAMP | damage-associated molecular pattern |
| DIAST-CHF | Diastolic Dysfunction in Heart Failure |
| DNA | deoxyribonucleic acid |
| Drp1 | dynamin-related protein 1 |
| dROMs | derivatives of reactive oxygen metabolites |
| E/A | ratio of early to late transmitral flow velocities |
| E/e′ | ratio of early mitral inflow velocity to early diastolic mitral annular velocity |
| ECV | extracellular volume fraction |
| ELISA | enzyme-linked immunosorbent assay |
| EMPEROR-Reduced | Empagliflozin Outcome Trial in Patients with Chronic Heart Failure and a Reduced Ejection Fraction |
| eNOS | endothelial nitric oxide synthase |
| ERK1/2 | extracellular signal-regulated kinase 1/2 |
| ETC | electron transport chain |
| F2-isoprostanes | F2-isoprostanes |
| Gal-3 | galectin-3 |
| Gal-3C | galectin-3 C-terminal domain |
| GDF-15 | growth differentiation factor 15 |
| GLM | generalized linear model |
| GLS | global longitudinal strain |
| GPX4 | glutathione peroxidase 4 |
| GSH | glutathione |
| HF | heart failure |
| HFmrEF | heart failure with mildly reduced ejection fraction |
| HFpEF | heart failure with preserved ejection fraction |
| HFrEF | heart failure with reduced ejection fraction |
| HIF-1α | hypoxia-inducible factor 1-alpha |
| Hmox1 | heme oxygenase 1 |
| HPLC | high-performance liquid chromatography |
| hs-cTn | high-sensitivity cardiac troponin |
| hs-cTnT | high-sensitivity cardiac troponin T |
| hs-CRP | high-sensitivity C-reactive protein |
| IFN-β | interferon beta |
| IKKβ | inhibitor of nuclear factor kappa-B kinase subunit beta |
| IL-1β | interleukin-1 beta |
| INOCA | ischemia with no obstructive coronary artery disease |
| iNOS | inducible nitric oxide synthase |
| IRF3 | interferon regulatory factor 3 |
| JNK | c-Jun N-terminal kinase |
| LA | left atrial |
| LAVI | left atrial volume index |
| LGE | late gadolinium enhancement |
| LV | left ventricular |
| LVEDP | left ventricular end-diastolic pressure |
| LVEF | left ventricular ejection fraction |
| LVMI | left ventricular mass index |
| M2 | type 2/alternatively activated macrophage phenotype |
| MAPK | mitogen-activated protein kinase |
| MDA | malondialdehyde |
| MFF | mitochondrial fission factor |
| Mfn1/2 | mitofusin 1/2 |
| mGPX4 | mitochondrial glutathione peroxidase 4 |
| MPI | myocardial performance index |
| MitoQ | mitochondria-targeted ubiquinone/mitoquinone |
| MPO | myeloperoxidase |
| MPRI | myocardial perfusion reserve index |
| mPTP | mitochondrial permeability transition pore |
| mtDNA | mitochondrial DNA |
| mTOR | mechanistic target of rapamycin |
| MTP-131 | mitochondria-targeted peptide 131/elamipretide |
| mtROS | mitochondria-derived reactive oxygen species |
| Na+ | sodium ion |
| NAD+ | nicotinamide adenine dinucleotide |
| NADPH | nicotinamide adenine dinucleotide phosphate |
| NCX | sodium–calcium exchanger |
| NF-κB | nuclear factor kappa B |
| NHE1 | sodium–hydrogen exchanger 1 |
| NLRP3 | NOD-like receptor family pyrin domain containing 3 |
| NO | nitric oxide |
| NOX | NADPH oxidase |
| NOX2 | NADPH oxidase 2 |
| NOX4 | NADPH oxidase 4 |
| Nrf2 | nuclear factor erythroid 2-related factor 2 |
| NT-proBNP | N-terminal pro-B-type natriuretic peptide |
| NYHA | New York Heart Association |
| OPA1 | optic atrophy 1 |
| OSI | oxidative stress index |
| PA | pulmonary artery |
| p38-MAPK | p38 mitogen-activated protein kinase |
| PASP | pulmonary artery systolic pressure |
| PKC | protein kinase C |
| PSH | protein sulfhydryl groups |
| PUFA | polyunsaturated fatty acid |
| RAGE | receptor for advanced glycation end products |
| RIRR | ROS-induced ROS release |
| ROC | receiver operating characteristic |
| ROS | reactive oxygen species |
| RV | right ventricle |
| RV–PA | right ventricular–pulmonary arterial |
| RyR2 | ryanodine receptor 2 |
| s′ | tissue Doppler systolic annular velocity |
| SGLT2 | sodium–glucose cotransporter 2 |
| SHp | serum thiol groups |
| SIRT1 | sirtuin 1 |
| SIRT3 | sirtuin 3 |
| SLC7A11 | solute carrier family 7 member 11 |
| Smad2/3 | small mothers against decapentaplegic 2/3 |
| SOD2 | superoxide dismutase 2 |
| SS-31 | elamipretide |
| sST2 | soluble suppression of tumorigenicity 2 |
| System xc− | cystine/glutamate antiporter system xc− |
| TAC | total antioxidant capacity |
| TAPSE | tricuspid annular plane systolic excursion |
| TAS | total antioxidant status |
| TBARS | thiobarbituric acid reactive substances |
| TBK1 | TANK-binding kinase 1 |
| TGF-β | transforming growth factor beta |
| TOS | total oxidant status |
| VDAC | voltage-dependent anion channel |
| VDAC1 | voltage-dependent anion channel 1 |
| VO2max | maximal oxygen uptake |
| WISE-CVD | Women’s Ischemia Syndrome Evaluation–Coronary Vascular Dysfunction |
| XOR | xanthine oxidoreductase |