Table 1.

Mean [95% confidence interval] circulating levels of steroid hormones and DHEAS in PA and control female rhesus monkeys before and after i.m. injection of 0.5 mg/kg dexamethasone.

	Control female monkeys			PA female monkeys
Steroid	Before dexamethasone	After dexamethasone	P value (≤)	Before dexamethasone	After dexamethasone	P value (≤)
17OHP4	0.57 [0.26, 1.24]	0.07 [0.03, 0.18]	0.001	0.31 [0.14, 0.68]	0.05 [0.02, 0.14]	0.002
Cortisol	30.41 [26.39, 35.04]	5.21 [4, 6.78]	0.001	29.17 [19.56, 43.51]	7.31 [4.94, 10.82]	0.01
DHEA	3.27 [1.96, 5.44]	0.29 [0.17, 0.51]	0.001	8.26 [4.96, 13.76]a	3.07 [1.79, 5.27]b	0.006
DHEAS	4.82 [2.79, 8.3]	6.5 [3.84, 11.01]	NS	4.31[2.93, 6.36]	3.98 [2.23, 7.1]	NS
A	177 [132, 239]	107 [70, 163]	NS	257 [190, 345]	131 [86, 200]	NS
Corticosterone	2.01 [1.24, 3.26]	0.68 [0.54, 0.85]	0.007	2.56 [1.33, 4.93]	1.08 [0.59, 1.99]	NS
Testosterone	0.21 [0.14, 0.29]	0.08 [0.05, 0.14]	0.006	0.30 [0.21, 0.43]	0.07 [0.04, 0.12]	0.004

^ap≤0.03, versus control females before dexamethasone;

^bp<0.001 versus control females after dexamethasone. Units used: 17OHP4 (17α- hydroxyprogesterone, ng/ml), cortisol (mg/dl), DHEA (ng/ml), DHEAS (μg/dl), A (Androstenedione pg/ml), Corticosterone (ng/ml), Testosterone (ng/ml). Conversion to SI units, 17α- hydroxyprogesterone*3.0257 nmol/L, Cortisol*27.59 nmol/L, DHEA*3.47 nmol/L, DHEAS*0.02714 μmol/L, Androstenedione*3.49 pmol/L, Corticosterone*2.886 nmol/L, Testosterone*3.47 nmol/L.