Fig. 4.
Multiple sequence alignment of DSX homologues from D. melanogaster, B. tryoni, M. domestica, M. scalaris, B. mori and A. gambiae. The sequence is divided into: (A) the region that is common to DSXF and DSXM; (B) the conserved female-specific parts; (C) the highly divergent male-specific regions. The DBD/OD1 and OD2 domains are indicated. Black boxes represent areas of amino acid identity; shaded boxes represent areas of amino acid similarity; the asterisks * indicate 6 amino acids whose replacement has been shown to abolish DNA-binding activity in D. melanogaster.