| AD | Alzheimer’s disease |
| Aβ | Amyloid beta peptide |
| Aβ1–42 | Amyloid beta 1–42 peptide |
| Aβ40/42 | Amyloid beta 40/42 isoforms |
| ABIOME | A Bioreactor Imitation of the Microbiota Environment |
| AChE | Acetylcholinesterase |
| ACFB | Artichoke, caihua, and fenugreek vegetal extract original blend |
| Ac-Tau | Acetylated tau protein |
| Adcyap1 | Adenylate cyclase-activating polypeptide 1 |
| AI | Artificial intelligence |
| AKT | Protein kinase B (PKB) |
| pAKT | Phosphorylated AKT |
| AKT1 | Protein kinase B alpha (PKBα) |
| ALPL | Alkaline phosphatase |
| AMPK | 5′ adenosine monophosphate-activated protein kinase |
| ANXA3 | Annexin A3 |
| AMPs | Antimicrobial peptides |
| APP | Amyloid precursor protein |
| APP/PS1 | Amyloid precursor protein/presenilin-1 transgenic mouse model |
| APP/PS2 | Amyloid precursor protein/presenilin-2 transgenic mouse model |
| AREs | Antioxidant-responsive elements |
| Arg1 | Arginasi 1 |
| ASC | Apoptosis-associated speck-like protein containing a CARD |
| ATG 5/7 | Autophagy-related 5/7 |
| BAX | Bcl2-associated X-protein |
| BALB/c | Bagg albino/c |
| Bcl2 | B-cell lymphoma 2 |
| BBB | Blood–brain barrier |
| BDNF | Brain-derived neurotrophic factor |
| BBM | Blood-based biomarker |
| BMECs | Brain microvascular endothelial cells |
| BUB1b | BUB1 mitotic checkpoint serine/threonine kinase B |
| BV2 | Immortalized murine microglial cell line derived from C57BL/6 mouse microglia |
| Calb1 | Calbindina 1 |
| Camk2g | Calcium/calmodulin-dependent protein kinase II gamma |
| CAT | Catalase |
| Cct4 | Chaperonin containing TCP1 subunit 4 |
| CD | Crohn’s disease |
| CD86 | Cluster of Differentiation 86 |
| CFP | Complement factor properdin |
| cGMP | Cyclic guanosine monophosphate |
| CNS | Central nervous system |
| COX-2 | Cyclooxygenase-2 |
| CSF | Cerebrospinal fluid |
| CTSK | Catepsina K |
| CREB | cAMP response element-binding protein |
| DSS | Dextran sodium sulfate |
| Endog | Endonuclease G |
| EP300 | E1A binding protein p300 |
| EphA2 | Ephrin type-A receptor 2 |
| EVs | Extracellular vesicles |
| FABP3 | Fatty acid-binding protein 3 |
| FOS | Fructooligosaccharides |
| FOXO | Forkhead box O |
| FOXO1 | Forkhead box protein O1 |
| GABA | Acido gamma-amminobutirrico |
| GAPDH | Gliceraldeide-3-fosfato deidrogenasi |
| γ-GCs | γ-glutamilcisteina sintetasi |
| GFs | Gingival fibroblasts |
| GLUT2 | Glucose transporter 2 |
| GOS | Galactooligosaccharides |
| GOT1 | Glutamate oxaloacetate transaminase 1 |
| GPX | Glutathione peroxidase |
| GPX4 | Glutathione peroxidase 4 |
| GSDMD | Gasdermin D |
| GSH | Glutathione |
| GSR | Glutathione reductase |
| Hbq1a | Hemoglobin, theta 1A |
| H2O2 | Hydrogen peroxide |
| HMGB1 | High-mobility group box 1 |
| HO-1 | Heme oxygenase-1 |
| HPG | Highly porous gold electrodes |
| hs-CRP | High-sensitivity C-reactive protein |
| H2S | Hydrogen sulfide |
| Hsp70 | Heat Shock Protein 70 |
| 5-HT | 5-hydroxytryptamine |
| IAA | Indole-3-acetic acid |
| IBD | Inflammatory bowel disease |
| ICA | Icariin |
| ICT | Icaritin |
| ICS | Icariside II |
| IEB | Intestinal epithelial barrier |
| IEC | Intestinal epithelial cells |
| IgA | Immunoglobulin A |
| iNOS | Inducible nitric oxide synthase |
| iNPH | Idiopathic normal pressure hydrocephalus |
| IL | Interleukin |
| IL-1β | Interleukin-1 beta |
| IL-4 | Interleukin-4 |
| IL-6 | Interleukin-6 |
| IL-8 | Interleukin-8 |
| IL-10 | Interleukin-10 |
| IL-12 | Interleukin-12 |
| IL-18 | Interleukin-18 |
| JNK | c-Jun N-terminal kinase |
| JPH3 | Junctophilin-3 |
| KDR | Kinase insert domain receptor |
| Keap1 | Kelch-like ECH-associated protein 1 |
| LASSO | Least Absolute Shrinkage Operator |
| LC3 | Microtubule-associated proteins 1A/1B light chain 3 |
| LDH | Layered double hydroxide |
| LPS | Lipopolysaccharide |
| MAP9 (Mtap9) | Microtubule-associated protein 9 |
| MAPK | Mitogen-activated protein kinase |
| MAPK14 | Mitogen-activated protein kinase 14 |
| MAPT | Microtubule-associated protein tau |
| MARS | Multivariate adaptive regression splines |
| MCI | Mild cognitive impairment |
| MDA | Malondialdehyde |
| MLKL | Mixed lineage kinase domain-like pseudokinase |
| MMP9 | Matrix metalloproteinase-9 |
| MNPs | Micro- and nanoplastics |
| MPs | Microplastics |
| mRNAs | Messenger RNAs |
| mTOR | Mechanistic target of rapamycin |
| mTORC1 | Mammalian/mechanistic target of rapamycin complex 1 |
| Muc2 | Mucin 2 |
| NAAA | N-acylethanolamine acid amide hydrolase |
| NAD+ | Nicotinamide adenine dinucleotide |
| NAT2 | N-acetyltransferase 2 |
| NCM460 | Human normal colon mucosal epithelial cell line |
| NF-κB | Nuclear factor kappa B |
| Nfe2l2 | Nuclear factor erythroid 2-related factor 2 gene |
| NfL | Neurofilament light chain |
| NH3 | Ammonia |
| NLRP3 | NOD-, LRR-, and pyrin domain-containing protein 3 inflammasome |
| NMN | Nicotinamide mononucleotide |
| NO | Nitric oxide |
| NPs | Nanoplastics |
| NQO1 | NAD(P)H quinone oxidoreductase 1 |
| Nrf2 | Nuclear factor erythroid 2-related factor 2 |
| OEB | Oral epithelial barrier |
| OFI | Opuntia ficus-indica |
| 8- OHdG | 8-Hydroxy-2′-deoxyguanosine |
| p53 | Tumor protein p53 |
| p62 | p62 protein or sequestosome-1 |
| p65 | Nuclear factor NF-kappa-B p65 subunit |
| p-p65 | Phosphorylated NF-κB p65 subunit |
| PD | Parkinson’s disease |
| PDE4B | Phosphodiesterase 4B |
| PE | Polyethylene |
| PEG | Polyethylene glycol |
| PET | Polyethylene terephthalate |
| Per1 | Period circadian regulator 1 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 |
| PGC-1α | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha |
| PGE2 | Prostaglandin E2 |
| PHA | Phytohemagglutinin |
| PIM2 | Proviral integration site for Moloney murine leukemia virus 2 |
| PI3K | Phosphoinositide 3-kinase |
| Pik3cg | Phosphoinositide-3-kinase catalytic gamma polypeptide |
| PLA2G1B | Phospholipase A2, group 1B |
| p-mTOR | Phosphorylated mechanistic target of rapamycin |
| Pot1α | Protection of telomeres 1 alpha |
| PP | Polypropylene |
| PPARγ | Peroxisome proliferator-activated receptor gamma |
| PRKCG | Protein kinase C gamma type |
| Prnp | Prion protein gene |
| PS | Polystyrene |
| PSA | Plasma scavenging activity |
| PS-COOH | Carboxyl-modified polystyrene microplastics |
| p-tau181 | Phosphorylated tau protein 181 |
| p-tau217 | Phosphorylated tau protein at threonine 217 residue |
| PTB | Pterostilbene |
| PTFS2 | Prostaglandin-endoperoxide synthase 2 |
| p-ULK1 | Phosphorylated Unc-51-like autophagy-activating kinase 1 |
| PVC | Polyvinyl chloride |
| QA | Quinic acid |
| RAGE | Receptor for advanced glycation end products |
| RANKL | Receptor activator of nuclear factor κB ligand |
| RhoA | Ras homolog family member A |
| ROS | Reactive oxygen species |
| RTP4 | Receptor transporter protein 4 |
| SCFAs | Short-chain fatty acids |
| SCG3 | Secretogranin-3 |
| SGLT1 | Sodium-glucose cotransporter 1 |
| SH-G | Sulfhydryl groups |
| SIRT1 | Sirtuin 1 |
| SIRT6 | Sirtuin 6 |
| SKN-1 | Skinhead-1 transcription factor |
| Slc7a5 | Solute carrier family 7 member 5 |
| SOD | Superoxide dismutase |
| SOD1 | Superoxide dismutase 1 (Cu/Zn superoxide dismutase) |
| SOD2 | Superoxide dismutase 2 or manganese superoxide dismutase |
| SNAC | Alpha-synuclein |
| SNAP25 | Synaptosome-associated protein 25 |
| SP | Spirulina (Arthrospira platensis) |
| SPP1 | Secreted phosphoprotein 1 |
| STAT3 | Signal transducer and activator of transcription 3 |
| SULT1A1 | Sulfotransferase 1A1 |
| Th1 | T helper 1 |
| Th2 | T helper 2 |
| Th17 | T helper 17 |
| TJs | Tight junction proteins |
| TLR-2 | Toll-like receptor 2 |
| TLR4 | Toll-like receptor 4 |
| TNF-α | Tumor necrosis factor alpha |
| TPI1 | Triosephosphate isomerase 1 |
| Tregs | Regulatory T cells |
| Trx | Thioredoxin |
| UC | Ulcerative colitis |
| UGT2B4 | UDP-glucuronosyltransferase family 2 member B4 |
| ULK1 | Unc-51-like autophagy-activating kinase 1 |
| UVA | Ultraviolet A |
| Vegfd (Figf) | Vascular endothelial growth factor D |
| VGF | Nerve growth factor-inducible |
| Zfand5 | Zinc finger AN1-type containing 5 |
| ZO-1 | Zonula occludens-1 |