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Plasma concentrations versus time profiles of tritiated [3H] paclitaxel upon intravenous administration to SKOV-3 human ovarian adenocarcinoma-bearing nude mice. Paclitaxel was administered in aqueous solution as control (^), in poly(ethylene oxide)-modified poly(ɛ-caprolactone) nanoparticles (▪), and poly(ethylene oxide)-modified poly(β-amino ester) (PbAE) nanoparticles (▴).
