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Tumor concentrations as a function of time of uptake of tritiated [3H] paclitaxel upon intravenous administration to SKOV-3 human ovarian adenocarcinoma-bearing nude mice. Paclitaxel was administered intravenously in aqueous solution as control, in poly(ethylene oxide)-modified poly(ɛ-caprolactone) nanoparticles (PCL), and poly(ethylene oxide)-modified poly(β-amino ester) (PbAE) nanoparticles.
