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. 2026 Aug 11;15(8):993. doi: 10.3390/antiox15080993
4-HNE 4-hydroxynonenal
ABCG2 ATP-binding cassette subfamily G member 2
ACSL4 acyl-CoA synthetase long-chain family member 4
AIM2 absent in melanoma 2
ALOX15 arachidonate 15-lipoxygenase
ASC apoptosis-associated speck-like protein containing a CARD
ATP adenosine triphosphate
CD38 cluster of differentiation 38
citH3 citrullinated histone H3
CRP C-reactive protein
CXCR2 C-X-C chemokine receptor 2
DECT dual-energy computed tomography
dHL-60 differentiated HL-60 cells
eGFR estimated glomerular filtration rate
ERK extracellular signal-regulated kinase
ESR erythrocyte sedimentation rate
FEUA fractional excretion of uric acid
FTH1 ferritin heavy chain 1
GBD Global Burden of Disease
GPX4 glutathione peroxidase 4
GSH reduced glutathione
GSS glutathione synthetase
GSSG glutathione disulfide
HO-1 heme oxygenase 1
Hs-CRP High-sensitivity C-reactive protein
IL-1β interleukin-1 beta
IL-6 interleukin-6
IL-8 interleukin-8
IL-18 interleukin-18
IRF5 Interferon regulatory factor 5
KEAP1 Kelch-like ECH-associated protein 1
LPS lipopolysaccharide
MDA malondialdehyde
MPO myeloperoxidase
mtDNA Mitochondrial DNA
MSU monosodium urate
MyD88 myeloid differentiation primary response 88
NAD+ Oxidized nicotinamide adenine dinucleotide
NETs neutrophil extracellular traps
NF-κB nuclear factor kappa B
NLRP3 NOD-like receptor family pyrin domain-containing 3
NOX NADPH oxidase
Nrf2 nuclear factor erythroid 2-related factor 2
P2X7R P2X purinoceptor 7
P2Y6R P2Y purinoceptor 6
PAD4 peptidyl arginine deiminase 4
PBMCs peripheral blood mononuclear cells
ROS reactive oxygen species
RIS Research information systems citation format
SHP-1 Src homology region 2 domain-containing phosphatase 1
SOD superoxide dismutase
SOCS suppressor of cytokine signaling
Syk spleen tyrosine kinase
TNF-α tumor necrosis factor alpha
THP-1 Human monocytic leukemia cell line
ULT urate-lowering therapy
URAT1 urate transporter 1 (SLC22A12)
VDAC2 voltage-dependent anion channel 2
XDH xanthine dehydrogenase
XOI xanthine oxidase inhibitor
XOR xanthine oxidoreductase