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. Author manuscript; available in PMC: 2006 Jan 25.
Published in final edited form as: Blood. 2004 Dec 21;105(7):2973–2978. doi: 10.1182/blood-2004-09-3660

Table 3.

Univariate analysis of patient, donor, and transplantation characteristics and subsequent development of H–Y antibodies

≥1 H–Y antibody detected
Transplantation characteristics Yes n = 39 (%) No n = 36 (%) P
Primary disease .64*
 Acute myeloid leukemia 9 8
 Acute lymphoblastic leukemia 4 4
 Chronic myeloid leukemia 11 8
 Chronic lymphocytic leukemia 3 2
 Myelodysplastic syndrome 5 6
 Non-Hodgkin lymphoma 4 6
 Hodgkin disease 2 0
 Multiple myeloma 1 1
 Other 0 1
Good prognosis > .99
 Yes 16 (41) 15 (42)
 No 23 (59) 21 (58)
Patient age .69
 Median (range), y 45 (19-59) 44 (19-66)
Donor age .58
 Median (range), y 39 (16-69) 39 (14-69)
HSC donor .06
 HLA-matched related 29 (74) 19 (53)
 HLA-matched unrelated 6 (15) 13 (36)
 HLA-mismatched related 1 (3) 2 (6)
 HLA-mismatched unrelated 3 (8) 2 (6)
HSC source .82
 Bone marrow 22 (56) 22 (61)
 Peripheral blood stem cells 17 (44) 14 (39)
Stem cell processing .39
 Unmanipulated 33 (85) 27 (75)
 T-cell depleted 6 (15) 9 (25)
Conditioning regimen .61
 Myeloablative 29 (74) 24 (67)
 Nonmyeloablative 10 (26) 12 (33)
*

Comparison between acute myeloid leukemia/myelodysplastic syndrome/chronic myeloid leukemia (myeloid diseases) versus all other disease categories.

Comparison between matched related versus matched unrelated.