3-MP	3-mercaptopyruvate
3-MST	3-mercaptopyruvate sulfurtransferase
6MWD	six-minute walk distance
α-SMA	alpha-smooth muscle actin
BMPR2	bone morphogenetic protein receptor type 2
cAMP	cyclic adenosine monophosphate
CAT	cysteine aminotransferase
CBS	cystathionine β-synthase
cGMP	cyclic guanosine monophosphate
COPD	chronic obstructive pulmonary disease
CSE	cystathionine γ-lyase
CTH	gene encoding CSE
DATS	diallyl trisulfide
DTT	dithiothreitol
EC50	half-maximal effective concentration
ECM	extracellular matrix
eNOS	endothelial nitric oxide synthase
ERA	endothelin receptor antagonist
ERK	extracellular signal-regulated kinase
ETAR	endothelin receptor type A
ETBR	endothelin receptor type B
H2S	hydrogen sulfide
H3K9ac	acetylated histone H3 lysine 9
H3K9me3	trimethylated histone H3 lysine 9
HDAC	histone deacetylase
HDACi	histone deacetylase inhibitor
IP receptor	prostacyclin receptor
IP3	inositol trisphosphate
iPAH	idiopathic pulmonary arterial hypertension
MCT	monocrotaline
MMP	matrix metalloproteinase
mPAP	mean pulmonary arterial pressure
mRNA	messenger RNA
NAC	N-acetylcysteine
NaHS	sodium hydrosulfide
Na2S	sodium sulfide
NT-proBNP	N-terminal pro-brain natriuretic peptide
O2	oxygen
ONOO−	peroxynitrite
PAEC	pulmonary arterial endothelial cell
PAH	pulmonary arterial hypertension
PASMC	pulmonary arterial smooth muscle cell
PDE5	phosphodiesterase-5
PDE5i	phosphodiesterase-5 inhibitor
PECAM-1	platelet endothelial cell adhesion molecule-1
PIP3	phosphatidylinositol (3,4,5)-trisphosphate
PKA	protein kinase A
PKG	protein kinase G
PTEN	phosphatase and tensin homolog
PVR	pulmonary vascular resistance
ROS	reactive oxygen species
SAHA	suberoylanilide hydroxamic acid (vorinostat)
siRNA	small interfering RNA
SOD	superoxide dismutase
Sp1	specificity protein 1
TSA	trichostatin A
TTCW	time to clinical worsening
VCAM-1	vascular cell adhesion molecule-1