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. Author manuscript; available in PMC: 2006 Oct 28.
Published in final edited form as: J Biol Chem. 2005 Aug 26;280(43):36529–36540. doi: 10.1074/jbc.M503111200

Figure 3. RNAi knockdown of uPA and uPAR expression inhibits the invasive potential of PC3 cells.

Figure 3

A. The invasive potential of mock and cells transfected with the indicated shRNA plasmids were examined by matrigel invasion assay (visual field representative of one experiment). Invasion assays performed as described above (see Fig. 1C).

B. Representative number of invading cells through the matrigel was counted under microscope in three random fields at 200X. Each bar represents the mean ± SD of three fields counted. Significant difference from controls (i.e., mock or scrambled vector-transfected cells) is indicated by asterisks * (P <0.05).

(Results are representative of three separate experiments.)