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. 2002 Jun;184(12):3401–3405. doi: 10.1128/JB.184.12.3401-3405.2002

TABLE 3.

Classification of phosphatases

Phosphatase class Characteristic
Taxonomic range Subunit size (kDa) Oligomerization Fold type Sequence motif(s)
FBPase I Eukarya, bacteria ∼38 Tetramer Sugar phosphatase FBPase, IMP 1
FBPase II Bacteria ∼36 Dimer Unknown None
FBPase III Bacteria ∼76 Tetramer Unknown None
FBPase IVa Archaea, HT bacteria ∼28 Dimerb Sugar phosphatase IMP 1, IMP 2
I-1-Pasec Eukarya, bacteria ∼30 Dimer Sugar phosphatase IMP 1, IMP 2
a

FBPase IV enzymes are at least present in the euryarchaea P. furiosus (AF453319), Pyrococcus horikoshii (PH1897), Pyrococcus abyssi (PAB0189), Methanococcus jannaschii (MJ0109), Archaeoglobus fulgidus (AF2372), Methanosarcina barkeri (MB1918), and Methanobacterium thermoautotrophicum (MTH871) and the hyperthermophilic (HT) bacteria Thermotoga maritima (TM1415) and Aquifex aeolicus (AQ1983).

b

The T. maritima enzyme is an exception, having a tetrameric structure.

c

Bacterial extragenic suppressor proteins (SuhB) are classified within the I-1-Pase family (3) and show I-1-Pase but not FBPase activity (20).