TABLE 3.
Phosphatase class | Characteristic
|
||||
---|---|---|---|---|---|
Taxonomic range | Subunit size (kDa) | Oligomerization | Fold type | Sequence motif(s) | |
FBPase I | Eukarya, bacteria | ∼38 | Tetramer | Sugar phosphatase | FBPase, IMP 1 |
FBPase II | Bacteria | ∼36 | Dimer | Unknown | None |
FBPase III | Bacteria | ∼76 | Tetramer | Unknown | None |
FBPase IVa | Archaea, HT bacteria | ∼28 | Dimerb | Sugar phosphatase | IMP 1, IMP 2 |
I-1-Pasec | Eukarya, bacteria | ∼30 | Dimer | Sugar phosphatase | IMP 1, IMP 2 |
FBPase IV enzymes are at least present in the euryarchaea P. furiosus (AF453319), Pyrococcus horikoshii (PH1897), Pyrococcus abyssi (PAB0189), Methanococcus jannaschii (MJ0109), Archaeoglobus fulgidus (AF2372), Methanosarcina barkeri (MB1918), and Methanobacterium thermoautotrophicum (MTH871) and the hyperthermophilic (HT) bacteria Thermotoga maritima (TM1415) and Aquifex aeolicus (AQ1983).
The T. maritima enzyme is an exception, having a tetrameric structure.