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. Author manuscript; available in PMC: 2006 Jan 25.
Published in final edited form as: J Med Chem. 2005 Oct 6;48(20):6236–6249. doi: 10.1021/jm0503547

Figure 3.

Figure 3

Inhibition of E-rosette formation by synthetic peptides derived from CD2 protein. Peptides were added to AET-treated sheep red blood cells (expressing CD58 protein) first, and then an equal amount of Jurkat cells (expressing CD2 protein) was added later. The cells were pelleted by centrifugation and incubated at 4 °C. The cell pellet was gently resuspended before the E-rosettes were counted. Cells with three or more SRBCs bound were counted as rosettes. At least 200 cells were counted to determine the percentage of E-rosette cells. Values are the percent inhibition of peptide-treated cells and expressed as the mean of three independent experiments.