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. Author manuscript; available in PMC: 2006 Jan 25.

Published in final edited form as: Oncogene. 2005 Jul 21;24(31):4993–4999. doi: 10.1038/sj.onc.1208683

Fig. 5 — Bortezomib-induced Bik/NBK accumulation and apoptosis different cancer cell lines. (A) Bortezomib-induced Bik/NBk accumulation. Cells were treated with 1 μM bortezomib (+) for 6 hours and harvested for Western blotting. Control cells (−) received no bortezomib. Data represent one of two independent experiments with similar results. (B) IC₅₀ determined by XTT assay at 4 days for the six cell lines listed in (A). (1) Lovo; (2) SW620; (3) HCT116; (4) DLD1; (5) SKVO3; (6) H1299.

Fig. 5 — Bortezomib-induced Bik/NBK accumulation and apoptosis different cancer cell lines. (A) Bortezomib-induced Bik/NBk accumulation. Cells were treated with 1 μM bortezomib (+) for 6 hours and harvested for Western blotting. Control cells (−) received no bortezomib. Data represent one of two independent experiments with similar results. (B) IC₅₀ determined by XTT assay at 4 days for the six cell lines listed in (A). (1) Lovo; (2) SW620; (3) HCT116; (4) DLD1; (5) SKVO3; (6) H1299.