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. Author manuscript; available in PMC: 2006 Jan 26.
Published in final edited form as: J Hypertens Suppl. 1997 Jan;15(1):S9–23. doi: 10.1097/00004872-199715011-00002

Fig. 8.

Fig. 8

Area under the curve for glucose tolerance tests in lean spontaneously hypertensive rats (SHR) and obese SHR (SHROB) phenotypes with and without chronic moxonidine treatment for (a) glucose and (b) insulin. Glucose tolerance curves presented were analyzed for area using the trapezoidal method (Prism program, GraphPAD). Note that insulin areas under the curve are plotted on a logarithmic scale to facilitate comparisons between groups. Data were analyzed by using a two-way analysis of variance by phenotype and drug treatment and Newman–Keuls post-hoc analysis. *Significant effect of phenotype, with SHROB > SHR in all cases except glucose area under the curve after moxonidine treatment, where SHROB < SHR. †Significant effect of moxonidine treatment, with glucose area under the curve being significantly decreased by moxonidine in SHROB and insulin area under the curve increased by moxonidine in both SHROB and in SHR.