NSCLC	Non-small cell lung cancer
ER	Estrogen receptor
ERα	Estrogen receptor alpha
ERβ	Estrogen receptor beta
E2	17-Beta-estradiol
EVs	Extracellular vesicles
TME	Tumor microenvironment
TGF-β	Transforming growth factor beta
IL-6	Interleukin 6
IL-8	Interleukin 8
CCXL-16	(C-X-C Motif) ligand 16 chemokine
PHTPP	4-[2-Phenyl-5,7-bis(trifluoromethyl)pyrazolo [1,5-a]pyrimidin-3-yl]phenol
MPP	1,3-Bis(4-hydroxyphenyl)-4-methyl-5-[4-(2-piperidin-1-ylethoxy)phenol]-1H-pyrazole
EMT	Epithelial–mesenchymal transition process
CDDP	Cisplatin
CAFs	Cancer-associated fibroblasts
FAP	Fibroblast-activated protein
PDGFR-β	Platelet-derived growth factor receptor-beta
PDPN	Podoplanin
α-SMA	Alpha smooth muscle actin
EGFR	Epidermal growth factor receptor
NFkB	Nuclear factor kappa-light-chain-enhancer of activated B cells
ERK	Extracellular signal-regulated kinase