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. Author manuscript; available in PMC: 2006 Jan 26.
Published in final edited form as: Apoptosis. 2005 Dec;10(6):1305–1315. doi: 10.1007/s10495-005-2138-y

Table 2.

Epithelial cell apoptosis and crypt-villus dimensions

Group EC Apoptosisa (%) Villus height (μm) Crypt depth (μm)
Non-operated Control 1.6 ± 0.7 310 ± 42 93 ± 18
Sham 2.7 ± 1.0 353 ± 40 77 ± 10
Sham+ACE-I 1.9 ± 0.4 340 ± 20 87 ± 6
SBS 4.3 ± 1.3* 556 ± 66* 113 ± 14*
SBS+ACE-I 1.8 ± 0.5 552 ± 56* 145 ± 22

Summary (mean ±SD, from at least 6 mice per group) of results of ACE-inhibitor (ACE-I) studies. Sham+ACE-I was used as an additional control to assess the effects of ACE-I in the absence of a SBS.

a

Results of TUNEL analysis (number of apoptotic cells per 100 epithelial cells).

Abbreviations: IEL, intraepithelial lymphocytes; ACE-I angiotensin converting enzyme inhibitor; EC, epithelial cells.

*

P<0.05 sham vs. SBS

P<0.05 Sham vs. Sham + ACE-I

P<0.05 SBS vs. SBS+ACE-I.