Table 3.
Group | ANG II receptor, type 1a | ANG II receptor, type 1b | ANG II receptor, type 2 |
---|---|---|---|
Sham | 0.13 ±0.14 | 0.14 ±0.17 | 0.41 ± 0.19 |
SBS | 0.05 ± 0.05 | 0.14 ± 0.03 | 0.44 ± 0.09 |
SBS+ACE-I | 0.03 ± 0.03 | 0.03 ± 0.03† | 0.30 ± 0.20* |
Expression of the ANGII receptor type 1a and 2 were significantly decreased with administration of ACE-I (P<0.05 for SBS vs. SBS + ACE-I). Data are from semi-quantitative RT-PCR based on the relative expression of the target gene to beta actin expression (mean ±SD, N=6).
P<0.05 for SBS+ACE-I group vs. SBS group.
P=0.001 for SBS+ACE-I group vs. SBS group.