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Summary of the major findings of ACE-I action after SBS formation
| Parameter studied after formation of SBS | Action of ACE-I |
|---|---|
| Crypt-villus architecture | Increased crypt depth |
| Epithelial cell apoptosis | Decreased |
| Epithelial cell apoptosis in TNF-α knockout mice | No effect |
| Epithelial cell proliferation | Increased |
| ACE expression | Increased |
