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Summary of the characterization of the human the p21(waf1/cip1) promoter by ChIP, gelshift and reporter gene assays
| Region no. | p53 ChIP | VDR ChIP | Functional p53-RE | Functional VDRE | Response to 5-fluorouracil | Response to 1α,25(OH)2D3 | CoA binding in re-ChIP |
|---|---|---|---|---|---|---|---|
| 1 (TSS) | + | + | − | − | − | − | + |
| 3 | − | − | − | − | − | − | − |
| 5 | + | − | + | − | + | − | ND |
| 7 | + | + | + | + | + | + | + |
| 12/12C | + | + | + | + | + | + | + |
| 19 | − | + | − | + | − | + | + |
