1-PPA	1-piperidine propionic acid
AUC	Area under the concentration–time curve
BBB	Blood–brain barrier
C/EBP-β	CCAAT enhancer-binding protein beta
CNS	Central nervous system
FBS	Fetal bovine serum
GSCs	Glioblastoma stem cells
H2O2	Hydrogen peroxide
HRP	Horseradish peroxidase
i.p.	Intra-peritoneal
MMPs	Matrix metalloproteinases
MRT	Median residence time
NCA	Non-compartmental analysis
PAR2	Protease-activated receptor 2
PK	pharmacokinetic
p.o.	Per os
RWD	Relative Wound Density
SD	Standard deviation
SEM	Standard error of the mean
TME	Tumor microenvironment
TMZ	Temozolomide
UPS	Ubiquitin-proteasome system