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Role of the AcrAB-TolC efflux pump and its activating pathways in the development of resistance of icdA mutants to nalidixic acid. •, icdA RH1854; ▪, wild-type (RH1854); ▾, ΔacrAB (RBH1855); ○, icdA ΔacrAB (icdA RBH1855). Other strains are derivatives of icdA RBH1854. Additional mutations are marA (▴), rob (▿), soxS (□), mar sox (⋄), and rob sox (▵).
