TABLE 1.
Clinical profiles and outcomes
| Characteristic | Mean ± SD (%) for:
|
Pa | ||
|---|---|---|---|---|
| Total | Preterm birth group | Control group | ||
| No. of women | 877 | 21 | 856 | |
| Age (yr) | 28.9 ± 4.6 | 29.6 ± 6.1 | 28.9 ± 4.5 | 0.500 |
| No. with age of <25 yr | 147 (16.8) | 4 (19.0) | 143 (16.7) | 0.999 |
| Gestation wk at entry | 8.6 ± 1.1 | 8.8 ± 1.4 | 8.6 ± 1.1 | 0.348 |
| Nulliparous | 482 (55.0) | 14 (66.7) | 468 (54.7) | 0.375 |
| BMI at entry of <19.8b | 347 (39.6) | 5 (23.8) | 342 (40.0) | 0.176 |
| Past history of preterm birth | 18 (2.1) | 3 (14.3) | 15 (1.8) | 0.007 |
| Antibiotic use at <22 wk for: | ||||
| C. trachomatis | 28 (3.2) | 0 (0.0) | 28 (3.3) | 0.999 |
| Other reasons | 102 (11.6) | 7 (33.3) | 95 (11.1) | 0.006 |
| Cervical cerclage | 19 (2.2) | 1 (4.8) | 18 (2.1) | 0.372 |
| Vaginal colonization with: | ||||
| M. genitalium | 7 (0.8) | 0 (0.0) | 7 (0.8) | 0.999 |
| M. hominis | 98 (11.2) | 4 (19.0) | 94 (11.0) | 0.280 |
| U. parvum | 456 (52.0) | 16 (76.2) | 440 (51.4) | 0.027 |
| U. urealyticum | 76 (8.7) | 1 (4.8) | 75 (8.8) | 0.999 |
| Any species of mycoplasma | 564 (64.3) | 19 (90.5) | 545 (63.7) | 0.010 |
| More than one mycoplasma species | 70 (8.0) | 2 (9.5) | 68 (7.9) | 0.681 |
| C. trachomatis and any species of mycoplasma | 22 (2.5) | 0 (0.0) | 22 (2.6) | 0.999 |
| C. trachomatis | 28 (3.2) | 0 (0.0) | 28 (3.3) | 0.999 |
| N. gonorrhoeae | 1 (0.1) | 0 (0.0) | 1 (0.1) | 0.999 |
a
Comparison between the preterm birth and control groups.
b
BMI = body weight/body height squared (kg/m2).