TABLE 1.
Fluconazole, griseofulvin, miconazole, isoconazole and clotrimazole in vitro susceptibility data for 92 dermatophyte isolates with different methods for inoculum preparation
| Tested agent | MIC data (μg/ml)
|
|||||||
|---|---|---|---|---|---|---|---|---|
| Filtered inocula
|
Nonfiltered inocula
|
|||||||
| Range | Ga | MIC50b | MIC90c | Range | Ga | MIC50b | MIC90c | |
| Fluconazole | 0.125->64.0 | 64.0 | 64.0 | >64.0 | 0.125->64.0 | >64.0 | >64.0 | >64.0 |
| Griseofulvin | 0.125-4.0 | 0.75 | 1.0 | 2.0 | 0.125-8.0 | 1.5 | 2.0 | 4.0 |
| Miconazole | 0.031-0.5 | 0.25 | 0.25 | 0.5 | 0.031-1.0 | 0.37 | 0.5 | 1.0 |
| Isoconazole | 0.031-0.5 | 0.09 | 0.0625 | 0.25 | 0.031-2.0 | 0.19 | 0.25 | 1.0 |
| Clotrimazole | 0.031-0.5 | 0.0625 | 0.0625 | 0.5 | 0.031-1.0 | 0.16 | 0.25 | 1.0 |
a
Geometric means.
b
MIC at which 50% of the isolates were inhibited.
c
MIC at which 90% of the isolates were inhibited.