Table 1.
3-D-pQCT Parameters in an Age-Stratified, Random Sample of Rochester, MN, Women (W) and Men (M)
Women |
Men |
p-values |
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---|---|---|---|---|---|---|---|---|---|---|
Change between 20 and 90 years |
Change between 20 and 90 years |
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Mean ± SD (20–29 years) (N = 17) | Absolute | Percentage | Age-Corr.* | Mean ± SD (20–29 years) (N = 19) | Absolute | Percentage | Age-Corr.* | M/W difference in young adults | M/W age difference† | |
Trabecular parameters | ||||||||||
BV/TV | 0.141 ± 0.028 | −0.039 | −27¶ | −0.27 | 0.178 ± 0.031 | −0.047 | −26¶ | −0.39 | 0.001 | 0.524 |
TbN (1/mm) | 2.64 ± 0.17 | −0.35 | −13¶ | −0.29 | 2.60 ± 0.25 | 0.17 | 7‡ | 0.02 | 0.577 | <0.001 |
TbTh (mm) | 0.053 ± 0.009 | −0.010 | −18¶ | −0.21 | 0.068 ± 0.008 | −0.018 | −24‡¶ | −0.43 | <0.001 | 0.010 |
TbSp (mm) | 0.327 ± 0.031 | 0.076 | 24¶ | 0.31 | 0.320 ± 0.041 | −0.007 | −2‡ | 0.11 | 0.531 | <0.001 |
Cortical parameters | ||||||||||
BA (mm2) | 235.3 ± 29.5 | 27.4 | 11§ | 0.16 | 355.9 ± 62.7 | 40.2 | 11§ | 0.16 | <0.001 | 0.458 |
BA (mm2/ht, m) | 143.9 ± 15.1 | 25.6 | 18¶ | 0.25 | 196.9 ± 29.9 | 37.8 | 19¶ | 0.28 | <0.001 | 0.201 |
EnA (mm2) | 176.5 ± 27.3 | 46.4 | 27¶ | 0.26 | 277.8 ± 62.0 | 52.8 | 19¶ | 0.21 | <0.001 | 0.713 |
EnA (mm2/ht, m) | 108.0 ± 15.1 | 35.5 | 34¶ | 0.33 | 153.6 ± 30.7 | 42.1 | 28¶ | 0.30 | <0.001 | 0.502 |
CTh (mm) | 0.825 ± 0.136 | −0.437 | −52‡¶ | −0.58 | 0.852 ± 0.176 | −0.320 | −38‡¶ | −0.40 | 0.603 | 0.001 |
Cort vBMD (mg/cm2) | 893.0 ± 45.2 | −192.7 | −22‡¶ | −0.64 | 850.3 ± 38.0 | −133.7 | −16‡¶ | −0.48 | 0.005 | <0.001 |
Where there was a significant relationship between height (Ht) and a given variable in young adults, both the unadjusted and adjusted values for all variables are given.
Pearson correlation coefficient.
Comparisons of slopes.
Indicates that regression model is nonlinear.
p < 0.01;
p < 0.001.
BV/TV, bone volume/tissue volume; TbN, trabecular number; TbTh, trabecular thickness; TbSp, trabecular separation; BA, bone area; EnA, endocortical area; CTh, cortical thickness; Cort vBMD, cortical volumetric BMD.