TABLE 3.
Subsystem | No. of reactions | No. of fluxes
|
No. of metabolites | No. of extreme pathways of type:
|
Total no. of pathways | Pathway/flux ratio | Total no. of H. influenzaee pathways | |||
---|---|---|---|---|---|---|---|---|---|---|
Internal | External | I | II | III | ||||||
A | 75 | 97 | 65 | 114 | 36 | 1 | 21 | 58 | 0.23 | 65 |
C | 34 | 55 | 38 | 48 | 50 | 1 | 17 | 68 | 0.55 | 83 |
L | 50 | 62 | 33 | 76 | 11 | 1 | 12 | 24 | 0.13 | 36 |
N | 68 | 105 | 49 | 86 | 51 | 8 | 36 | 95 | 0.38 | 764 |
T | 86 | 129 | 122 | 154 | 102 | 3 | 20 | 125 | 0.42 | 210 |
V | 75 | 80 | 45 | 113 | 16 | 1 | 5 | 22 | 0.14 | 21 |
Abbreviations for subsystems: A, amino acid biosynthesis and degradation; C, central or core metabolism; L, lipid and cell envelope biosynthesis; N, nucleotide biosynthesis and degradation; T, transport and energy-redox metabolism, (V) vitamin and cofactor biosynthesis. Pathways are classified according to the scheme presented in reference,63 wherein the primary metabolic pathways of functional significance are those of type I.