Skip to main content
. Author manuscript; available in PMC: 2006 Jan 27.
Published in final edited form as: Nature. 2005 May 5;435(7038):43–57. doi: 10.1038/nature03481

Figure 7. Microfilament system proteins.

Figure 7

Proteins with probable interactions with the actin cytoskeleton are tabulated by their documented or predicted functions. Coloured boxes indicate the presence of a protein related to the Dictyostelium (D) protein in metazoa (M), fungi (F) or plants (P). Dictyostelium-specific proteins have no recognizable relatives or differ from relatives due to extensions or unusual domain compositions. For details see Supplementary Information. Actin-binding modules: ADF, actin depolymerisation factor/cofilin-like domain; CH, calponin homology domain; EVH, Ena/VASP homology domain 2; FH2, formin homology 2 domain; GEL, gelsolin repeat domain; TRE, trefoil domain; KELCH, Kelch repeat domain; MYO, myosin motor domain; TAL, the I/LWEQ, actin-binding domain of talin and related proteins; VHP, villin head piece; WH2, Wiskott Aldrich syndrome homology region 2.