TABLE 3.
Spontaneous frameshift mutations involving homopolymeric repeats
| Strain | Gene | Mutationa | Positionb | Effect on gene expression |
|---|---|---|---|---|
| P833 | pspA | A(8) to A(7) | 538 | Truncation of PspA (amino acid 189 of 655) |
| P62 | spxB | A(6) to A(7) | 460 | Truncation of SpxB (amino acid 160 of 591) |
| P765 | xba | T(7) to T(8) | 959 | Restored expression of XbaI methylase |
| P806 | xba | T(8) to T(7) | 959 | Truncation of XbaI methylase (amino acid 335 of 361) |
a
Refers to the numbers of bases in homopolymeric repeats at the position noted.
b
Refers to the first base in the homopolymeric repeat relative to the first base in the initiation codon.