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Effect of CLDN-7 molecules upon infection of 293T cells by HIVNL4-3. A) HIVNL4-3 Env(-) virus infection of either CLDN-7211- or CLDN-7158-modified 293T cells. In experiment 1, HIV Env(-) at 50 ng of p24 was used to infect 104 cells in each well; in experiment 2, 104 cells were infected by virus at 100 ng of p24. B) HIVNL4-3 Env(+) virus infection of either CLDN-7211- or CLDN-7158-modified 293T cells. Plasmid pCDNA3-transfected 293T cells were also used as a control.
