FIG. 5.
Genetic organization of the Y. pseudotuberculosis AH locus containing the ypmA gene compared to the corresponding locus in Y. pestis CO92 biotype Orientalis (positions 285894 to 298332 of the genome sequence available under accession number AJ414151 [49]). Two hundred and fifty-base fragments were compared by using WU-Blast 2.0 software, and results were expressed as Blast scores. A score of 1250 represents 100% identity on 250 nucleotides. White arrows indicate Y. pestis ORFs that differ from Y. pseudotuberculosis ORFs. Shaded areas represent sequences common for Y. pestis and Y. pseudotuberculosis. Identical results were obtained when the Y. pseudotuberculosis AH sequence was compared with the genomic sequence of Y. pestis KIM5 strain P12 (http://www.genome.wisc.edu). Numbers on the Y. pestis sequence correspond to the annotation of the Y. pestis genome (49). yrs, Yersinia recombination site; bioD, dethiobiotine synthetase gene; IRl and IRr, left and right inverted repeats, respectively.