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. 2025 Nov 27;100(1):309–316. doi: 10.1038/s41390-025-04633-6

Table 4.

Secondary clinical outcomes.

HD (N = 279) LD (N = 304) Adjusted Risk ratio (95% CI) P-value
Time until complete EN (days) Mean (SD) 11.12 (5.13) 11.32 (5.6) — 0.924
Time with central catheter (days) Mean (SD) 12.79 (11.01) 13.12 (11.44) — 0.916
Duration of hospital stay Mean (SD) 50.22 (19.98) 53.06 (21.69) — 0.205
Sepsis N (%) 53 (18.9) 63 (20.7) 1.00 (0.73, 1.37) 0.994
Bronchopulmonary dysplasia N (%) 51 (18.7) 63 (20.7) 0.88 (0.66, 1.17) 0.374
Patent ductus arteriosus N (%) 45 (16.1) 69 (22.7) 1.22 (0.88,1.68) 0.237
Patent arteriosus ductus and sepsis N (%) 10 (3.7) 21 (7.2) 1.59 (0.78, 3.24) 0.203

Adjusted by gestational age and sex.

HD high dose, LD low dose, N number of patients, EN enteral nutrition.