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. 1982 Mar;195(3):270–273. doi: 10.1097/00000658-198203000-00005

Primary carcinoma of the gallbladder.

R E Hamrick Jr, F J Liner, P R Hastings, I Cohn Jr
PMCID: PMC1352630  PMID: 7059239

Abstract

The records of patients with primary carcinoma of the gallbladder treated at Charity Hospital, New Orleans, Louisiana, from 1965 through 1978 were reviewed. Eighty patients had histologically proven primary carcinoma of the gallbladder. Sixty-nine patients had sufficient data available for evaluation. Only one patient (1.4%) was clinically free of disease at five years. Surgical procedures were performed in 45 of the 69 patients. The remainder of the patients had their disease proved at autopsy. Thirty-five patients had widespread metastatic disease at the time of operation. None of these patients survived more than one year. Only 10 patients had potentially curable lesions. The diagnosis of carcinoma of the gallbladder was not made at operation in eight of these patients. The only five-year survivor was in this subgroup. This patient had papillary adenocarcinoma confined to the mucosa and muscularis, and had a cholecystectomy alone. This report reinforces the difficulty in diagnosis and the dismal prognosis for patients with primary carcinoma of the gallbladder. Intraoperative examination of the gallbladder, earlier operation for documented gallbladder disease, and more aggressive surgical therapy should improve survival figures.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Adson M. A. Carcinoma of the gallbladder. Surg Clin North Am. 1973 Oct;53(5):1203–1216. doi: 10.1016/s0039-6109(16)40147-7. [DOI] [PubMed] [Google Scholar]
  2. Arnaud J. P., Graf P., Gramfort J. L., Adloff M. Primary carcinoma of the gallbladder: review of 25 cases. Am J Surg. 1979 Sep;138(3):403–406. doi: 10.1016/0002-9610(79)90272-1. [DOI] [PubMed] [Google Scholar]
  3. Balaroutsos C., Bastounis E., Karamanakos P., Golematis B. Primary carcinoma of the gallbladder: analysis of 22 cases. Am Surg. 1974 Oct;40(10):605–608. [PubMed] [Google Scholar]
  4. Beltz W. R., Condon R. E. Primary carcinoma of the gallbladder. Ann Surg. 1974 Aug;180(2):180–184. doi: 10.1097/00000658-197408000-00009. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Gradisar I. A., Kelly T. R. Primary carcinoma of the gallbladder. Arch Surg. 1970 Mar;100(3):232–235. doi: 10.1001/archsurg.1970.01340210008003. [DOI] [PubMed] [Google Scholar]
  6. Hardy M. A., Volk H. Primary carcinoma of the gallbladder. A ten year review. Am J Surg. 1970 Dec;120(6):800–803. doi: 10.1016/s0002-9610(70)80053-8. [DOI] [PubMed] [Google Scholar]
  7. Klein J. B., Finck F. M. Primary carcinoma of the gallbladder. Review of 28 cases. Arch Surg. 1972 Jun;104(6):769–772. doi: 10.1001/archsurg.1972.04180060019004. [DOI] [PubMed] [Google Scholar]
  8. Maram E. S., Ludwig J., Kurland L. T., Brian D. D. Carcinoma of the gallbladder and extrahepatic biliary ducts in Rochester, Minnesota, 1935--1971. Am J Epidemiol. 1979 Feb;109(2):152–157. doi: 10.1093/oxfordjournals.aje.a112670. [DOI] [PubMed] [Google Scholar]
  9. Melson G. L., Reiter F., Evens R. G. Tumorous conditions of the gallbladder. Semin Roentgenol. 1976 Oct;11(3):269–282. doi: 10.1016/0037-198x(76)90035-3. [DOI] [PubMed] [Google Scholar]
  10. Olken S. M., Bledsoe R., Newmark H., 3rd The ultrasonic diagnosis of primary carcinoma of the gallbladder. Radiology. 1978 Nov;129(2):481–482. doi: 10.1148/129.2.481. [DOI] [PubMed] [Google Scholar]
  11. Piehler J. M., Crichlow R. W. Primary carcinoma of the gallbladder. Arch Surg. 1977 Jan;112(1):26–30. doi: 10.1001/archsurg.1977.01370010028005. [DOI] [PubMed] [Google Scholar]
  12. Piehler J. M., Crichlow R. W. Primary carcinoma of the gallbladder. Surg Gynecol Obstet. 1978 Dec;147(6):929–942. [PubMed] [Google Scholar]
  13. Ram M. D. Carcinoma of the gallbladder. Surg Gynecol Obstet. 1971 Jun;132(6):1044–1048. [PubMed] [Google Scholar]
  14. Ritchie J. K., Allan R. N., Macartney J., Thompson H., Hawley P. R., Cooke W. T. Biliary tract carcinoma associated with ulcerative colitis. Q J Med. 1974 Apr;43(170):263–279. [PubMed] [Google Scholar]
  15. Tanga M. R., Ewing J. B. Primary malignant tumors of the gallbladder: report of 43 cases. Surgery. 1970 Mar;67(3):418–426. [PubMed] [Google Scholar]

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