Figure 1:

CyTOF analysis. (A) Volcano plot of cellular subset differences among OA patients vs. healthy controls (HC). (B) Volcano plot of cellular subset differences within OA patient radiographic progressors (RP) vs. nonprogressors (NP). (C) Volcano plot of cellular subset differences within OA patient pain progressors (PP) vs. nonprogressors (NP). (D) Uniform manifold approximation and projection (UMAP) plot of all cellular populations using optsne algorithm. (E) UMAP of cellular populations different between OA and HC.