Table 4.
Antibiotic treatment and microbiological findings
| Variable | Total cohort (n = 39) |
|---|---|
| Infection type | |
| Spinal tuberculosis | 8 (20.5%) |
| Non-specific spinal infection | 31 (79.5%) |
| Anti-tuberculosis treatment | |
| Quadruple anti-tuberculosis therapy during hospitalization | 8 (20.5%) |
| Post-discharge oral anti-tuberculosis therapy for 12–18 months | 8 (20.5%) |
| Antibiotic treatment for non-specific spinal infection | |
| Cefoperazone-sulbactam-based regimen | 20/31 (64.5%) |
| Piperacillin-tazobactam-based regimen | 4/31 (12.9%) |
| Carbapenem-based regimen | 4/31 (12.9%) |
| Moxifloxacin-based regimen | 2/31 (6.5%) |
| Amikacin-based regimen | 1/31 (3.2%) |
| Vancomycin-containing regimen | 14/31 (45.2%) |
| Linezolid-containing regimen | 8/31 (25.8%) |
| Microbiological findings | |
| Positive blood culture | 2/39 (5.1%) |
| Positive tissue or pus culture | 2/39 (5.1%) |
| Any positive culture | 4/39 (10.3%) |
| Culture-negative cases | 35/39 (89.7%) |
| Identified pathogens | Salmonella spp.; Escherichia coli; Streptococcus gordonii |
Values are presented as n (%) or n/N (%). Percentages for antibiotic regimens for non-specific spinal infection were calculated using the 31 patients with non-specific infection as the denominator. Percentages for microbiological findings were calculated using the total cohort as the denominator. Some patients received combination therapy; therefore, antibiotic categories are not mutually exclusive