TABLE 3.

Binding and thermodynamic constants characterizing the interaction of pinensins A and B with Zn(II) and Cu(II) measured through ITC

Complex	N	KD (nM)	ΔH (kcal·mol−1)	ΔG (kcal·mol−1)	−TΔS (kcal·mol−1)
PinA+Zn(II)	0.675 ± 0.026	3.53 ± 2.84	−13.45 ± 0.07	−11.65 ± 0.49	1.81 ± 0.66
PinA+Cu(II)	0.747 ± 0.027	420 ± 175	1.82 ± 0.21	−8.73 ± 0.25	−10.55 ± 0.07
PinB+Zn(II)	0.738 ± 0.031	6.34 ± 4.19	−13.45 ± 0.21	−11.3 ± 0.42	2.18 ± 0.25
PinB+Cu(II)	0.646 ± 0.080	129 ± 21.9	1.51 ± 0.11	−9.42 ± 0.11	−10.9 ± 0.0