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. 2026 Sep 1;12:RP91792. doi: 10.7554/eLife.91792

Table 2. Demographics and clinical characteristics of Crohn’s disease cohorts.

Partial responder Full responder Not on anti-TNF
n = 5 n = 5 n = 4
Demographics and follow-up
Age at diagnosis (year) 12 (10–14) 12 (9–14) 15.5 (9–19)
Female sex 40% (2 patients) 40% (2 patients) 50% (2 patients)
Caucasian 80% (4 patients) 80% (4 patients) 50% (2 patients)
African American 0% (0 patient) 0% (0 patient) 0% (0 patient)
Native American or Alaskan Native 0% (0 patient) 0% (0 patient) 0% (0 patient)
Asian 0% (0 patient) 0% (0 patient) 0% (0 patient)
Mixed race 20% (1 patient) 0% (0 patient) 25% (1 patient)
Other 0% (0 patient) 20% (1 patient) 0% (0 patient)
Disease location/activity
Location
L1 0% (0 patient) 0% (0 patient) 0% (0 patient)
L2 0% (0 patient) 0% (0 patient) 0% (0 patient)
L3 100% (5 patients) 100% (5 patients) 75% (3 patients)
P modifier 20% (1 patient) 0% (0 patients) 25% (1 patient)
Behavior
B1 100% (5 patients) 100% (5 patients) 75% (3 patients)
B2 0% (0 patients) 0% (0 patients) 0% (0 patients)
B3 0% (0 patients) 0% (0 patients) 0% (0 patients)
Severity in wPCDAI 65
(35–77.5)
65
(22.5–87.5)
26.3
(15–57.5)
Medications
Mesalamine 0% (0 patient) 20% (1 patient) 50% (2 patients)
Azathioprine 20% (1 patient) 20% (1 patient) 25% (1 patient)
Methotrexate 80% (4 patients) 60% (3 patients) 0% (0 patient)
Anti-TNF 100% (5 patients) 100% (5 patients) 0% (0 patient)
Nutritional therapy 20% (1 patient) 20% (1 patient) 25% (1 patient)
Steroids 60% (3 patients) 60% (3 patients) 50% (2 patients)
Median time since diagnosis
Median 31.7
(29.6–37.2)
36.3
(29.6–37.2)
32
(24.2–33.7)