Table 1.
Distribution of clinical relevant antimicrobial resistance- and hypervirulence-associated genes on different plasmid types based on long-read sequencing of 32 isolates.
| HCI | SAMPLE ID | ST | Plasmid encoded relevant β-lactamase genes | Plasmid encoded clinical relevant aminoglycoside resistance-associated genes | Plasmid encoded hypervirulence-associated genes |
|---|---|---|---|---|---|
| A | 2023005581 | 147 | blaNDM-1 blaCTX-M-15 | aph(3′)-VI aac(6′)-Ib-cr | rmpA, rmpA2, iucA-D, iutA, peg344, shiF |
| 2024005307 | 147 | ||||
| 2024005406 | 147 | ||||
| C | 2023005619 | 147 | |||
| 2024005304 | 147 | aac(6′)-Ib10 | |||
| D | 2023005640 | 147 | |||
| G | 2024005107 | 147 | |||
| H | 2023005726 | 147 | |||
| I | 2023005445 | 147 | armA | ||
| J | 2024005244 | 147 | |||
| K | 2024005002 | 147 | |||
| 2024005238 | 147 | ||||
| A | 2022006260 | 147 | blaNDM-1 blaCTX-M-15 | armA | rmpA, rmpA2, iucA-D, iutA, peg344, shiF |
| aac(6′)-Ib-cr aac(6′)-Ib10 | |||||
| 2024005032 | 147 | blaNDM-1 blaCTX-M-15 | aph(3′)-VI | rmpA, rmpA2, iucA-D, iutA, peg344, shiF | |
| aac(6′)-Ib-cr | |||||
| aac(6′)-Ib-cr | |||||
| aac(6′)-Ib10 | |||||
| armA | |||||
| 2024005460 | 147 | blaNDM-1 blaCTX-M-15 | aph(3′)-VI | rmpA, rmpA2, iucA-D, iutA, peg344, shiF | |
| aac(6′)-Ib10 | |||||
| aac(6′)-Ib-cr | |||||
| bla CTX-M-15 | armA | ||||
| B | 2023005497 | 147 | blaNDM-1 blaCTX-M-15 | aph(3′)-VI | rmpA, rmpA2, iucA-D, iutA, peg344, shiF |
| aac(6′)-Ib-cr | |||||
| armA | |||||
| aac(6′)-Ib10 | |||||
| E | 2023006501 | 147 | blaNDM-5 blaCTX-M-15 | aph(3′)-VI | rmpA, rmpA2, iucA-D, iutA, peg344, shiF |
| aac(6′)-Ib9 | |||||
| 2024005104 | 147 | blaNDM-1 blaCTX-M-15 | aph(3′)-VI | rmpA, rmpA2, iucA-D, iutA, peg344, shiF | |
| aac(6′)-Ib-cr | |||||
| aac(6′)-Ib10 | |||||
| armA | |||||
| F | 2024005039 | 147 | blaNDM-1 blaCTX-M-15 | aac(6′)-Ib-cr armA | rmpA, rmpA2, iucA-D, iutA, peg344, shiF |
| 2022006141 | 147 | bla NDM-1 | aph(3′)-VI | rmpA, rmpA2, iucA-D, iutA, peg344, shiF | |
| 2024005162 | 147 | blaNDM-1 blaCTX-M-189 | aph(3′)-VI | rmpA, rmpA2, iucA-D, iutA, peg344, shiF | |
| aac(6′)-Ib-cr | |||||
| aac(6′)-Ib10 | |||||
| armA | |||||
| L | 2024005048 | 147 | bla NDM-1 | aph(3′)-VI armA | rmpA, rmpA2, iucA-D, iutA, peg344, shiF |
| 2024005049 | 147 | ||||
| N | 2022006053 | 107 | |||
| 2023005663 | 107 | ||||
| 2023005708 | 147 | ||||
| 2024005124 | 147 | ||||
| 2024005181 | 37 | ||||
| 2024005393 | 20 | ||||
| 2024005170 | 395 | bla NDM-1 | aph(3′)-VI armA | rmpA, rmpA2, iucA-D, iutA, peg344, shiF | |
| bla CTX-M-15 | aac(6′)-Ib-cr | ||||
| 2024005248 | 147 | bla NDM-1 | aph(3′)-VI armA | rmpA, rmpA2, iucA-D, iutA, peg344, shiF | |
| bla NDM-1 | aph(3′)-VI | ||||
| M | 2023005560 | 307 | bla NDM-1 | aph(3′)-VI armA | rmpA, rmpA2, iucA-D, iutA, peg344, shiF |
| bla CTX-M-15 | aac(6′)-Ib9 | ||||
| Colour | Plasmid type | ||||
| IncHI1B/IncFIB(Mar) | |||||
| IncHI1B/IncFIB(Mar)/IncR | |||||
| IncHI1B/ IncFIB(Mar)/IncFIB(pQil) | |||||
| IncFIB(K) | |||||
| IncFIB(pQil) | |||||
| IncR | |||||
| Not detected on the same contig of the listed antibiotic resistance gene of the Inc. plasmid group. | |||||
The first four digits indicate the sample year of isolates.