TABLE 2.

Imaging the surface structure of living cells^a

Organism	Observationsb	Reference
Saccharomyces cerevisiae	Low resolution; bud scars	22; this review (Fig. 3)
	In situ investigation of cell growth process	18
	High resolution; smooth surface	This review (Fig. 4)
Phanerochaete chrysosporium	High resolution: 10 nm; rodlet structures, changes upon germination	16
Aspergillus oryzae	High resolution: 10 nm; rodlet structures, changes upon germination	47
Lactococcus lactis	Sample deformation and imaging artifacts (holes, grooves)	9
Streptococcus salivarius	Smooth surface vs surface appendages (fibrils)	48
Pseudomonas aeruginosa	Surface morphology of biofilms; EPS	46
Pseudomonas putida	Surface morphology of biofilms; EPS	4

^aList of AFM studies in which living cells were investigated under aqueous solution without drying or chemical treatment.

^bEPS, extracellular polymeric substances.