表 2. Comparison of coagulation parameters between VTE and non-VTE groups before and after surgery.
VTE与非VTE患者术前后凝血指标比较
| Parameter | Time point | Non-VTE (n = 265) | t 1 | P 1 * | VTE (n = 42) | t 2 | P 2 † | t 3 | P 3 ‡ |
| PT: prothrombin time; APTT: activated partial thromboplastin time; TT: thrombin time; FIB: fibrinogen; PLT: platelet count; HGB: hemoglobin; Pre-op: preoperative; Post-op: postoperative. * represents paired t-test within the non-VTE group (Pre-op vs. Post-op); † represents paired t-test within the VTE group (Pre-op vs. Post-op); ‡ represents independent-samples t-test between groups (for the Pre-op rows, pre-op values are compared between groups; for the Post-op rows, post-op values are compared between groups). | |||||||||
| PT/s | Pre-op | 11.04 ± 0.73 | -7.476 | < 0.001 | 10.86 ± 0.52 | -6.519 | < 0.001 | 1.524 | 0.129 |
| Post-op | 11.51 ± 0.92 | 11.50 ± 0.63 | 0.116 | 0.908 | |||||
| APTT/s | Pre-op | 27.16 ± 2.24 | -2.023 | 0.044 | 26.53 ± 2.09 | -1.845 | 0.072 | 1.709 | 0.089 |
| Post-op | 27.52 ± 2.61 | 27.33 ± 2.64 | 0.421 | 0.674 | |||||
| TT/s | Pre-op | 16.70 ± 8.44 | 3.163 | 0.002 | 16.51 ± 1.08 | 7.218 | < 0.001 | 0.145 | 0.885 |
| Post-op | 15.04 ± 1.25 | 15.29 ± 0.97 | -1.222 | 0.223 | |||||
| FIB/(g/L) | Pre-op | 3.04 ± 1.49 | -8.363 | < 0.001 | 3.25 ± 0.96 | -10.385 | < 0.001 | -0.860 | 0.390 |
| Post-op | 4.03 ± 1.27 | 4.54 ± 1.41 | -2.399 | 0.017 | |||||
| D-dimer/(mg/L) | Pre-op | 0.63 ± 1.73 | -5.955 | < 0.001 | 0.61 ± 0.72 | -3.290 | 0.002 | 0.068 | 0.946 |
| Post-op | 1.40 ± 1.78 | 3.34 ± 5.41 | -4.528 | < 0.001 | |||||
| PLT/(× 109 L-1) | Pre-op | 230.69 ± 77.38 | 5.397 | < 0.001 | 215.60 ± 41.72 | 2.561 | 0.014 | 1.235 | 0.218 |
| Post-op | 212.25 ± 71.14 | 202.14 ± 47.30 | 0.889 | 0.375 | |||||
| HGB/(g/L) | Pre-op | 127.54 ± 17.97 | 15.200 | < 0.001 | 125.38 ± 15.72 | 7.986 | < 0.001 | 0.735 | 0.463 |
| Post-op | 115.68 ± 15.60 | 111.24 ± 13.13 | 1.747 | 0.082 | |||||