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. 2026 Aug 26;17:1897246. doi: 10.3389/fphar.2026.1897246

TABLE 1.

Main characteristics at baseline.

Indicators Support group (n = 67) Glucocorticoids group (n = 42) Nefecon group (n = 40) P Value
Gender ​ ​ ​ 0.798
Male [n (%)] 31 (46.3) 21 (50.0) 19 (47.5) ​
Female [n (%)] 36 (53.7) 21 (50.0) 21 (52.5) ​
Age (years) 46.92 ± 12.48 44.52 ± 11.83 46.55 ± 11.56 0.748
Hypertension [n (%)] ​ ​ ​ 0.313
Yes 29 (43.3) 15 (35.7) 18 (45.0) ​
No 38 (56.7) 27 (64.3) 22 (55.0) ​
Diabetes mellitus [n (%)] ​ ​ ​ 0.942
Yes 7 (10.4) 5 (11.9) 4 (10.0) ​
No 60 (89.6) 37 (88.1) 36 (90.0) ​
Smoking [n (%)] ​ ​ ​ 0.146
Yes 4 (6.0) 3 (7.1) 6 (15.0) ​
No 63 (94.0) 39 (92.9) 34 (85.0) ​
Alcohol consumption [n (%)] ​ ​ ​ 0.268
Yes 3 (4.5) 1 (2.4) 4 (10.0) ​
No 64 (95.5) 41 (97.6) 36 (90.0) ​
Hemoglobin (g/L) 137.95 ± 19.78 140.52 ± 18.76 136.89 ± 21.45 0.677
Platelets (×109/L) 248.62 ± 63.15 252.17 ± 60.89 245.98 ± 66.72 0.853
White blood cells (×109/L) 7.33 ± 2.67 7.56 ± 2.74 7.45 ± 2.78 0.923
Albumin (g/L) 40.15 ± 4.61 40.58 ± 4.37 40.02 ± 4.75 0.802
Fasting blood glucose (mmol/L) 5.19 ± 0.94 5.17 ± 0.90 5.15 ± 0.88 0.934
Serum creatinine (μmol/L) 103.18 ± 45.52 90.64 ± 41.13 105.87 ± 51.32 0.150
Estimated glomerular filtration rate (ml/min/1.73m2) 76.58 ± 29.08 86.64 ± 24.35 75.23 ± 28.76 0.166
24-h urinary protein quantification (g/d) 0.84 ± 0.89 0.82 ± 0.75 0.92 ± 1.15 0.692
24-h proteinuria (g/d), median (IQR) 1.16(IQR 0.56–1.19) 1.66(IQR 0.60–1.73) 2.42(IQR 1.29–2.78) 0.689
Urinary red blood cell count (/μl) 104.81 ± 205.68 102.64 ± 187.47 98.56 ± 168.34 0.877
Oxford classification
M 0/1 44/23 23/19 22/18 0.408
E 0/1 37/30 20/22 22/18 0.704
S 0/1 30/37 22/20 20/20 0.726
T 0/1/2 50/17/0 27/14/1 26/11/3 0.416
C 0/1/2 39/27/1 21/17/3 27/12/1 0.347