Skip to main content
. Author manuscript; available in PMC: 2026 Sep 3.
Published before final editing as: BMJ Qual Saf. 2026 Jul 12:bmjqs-2025-019061. doi: 10.1136/bmjqs-2025-019061

Table 3.

Patient Behavior (Calm versus Irritable), Stress from Uncertainty (SUS), and their Interaction as Predictors of Physicians’(A) Emotions and Engagement, (B) Assessments of Patients and Clinical Cases, and (C) Clinical Decisions, Behavior, and Diagnosis

Main Effects of SUS Main Effects of Patient Behavior SUS x Patient Behavior Interaction Effects
Coef.(SE) †† t p Coef.(SE) †† t p Coef. (SE) †† t p
A. Physicians’ Emotions and Engagement
 Anger† 2.67 (1.23) 2.17 0.11 31.61 (1.56) 20.21 <0.001 4.36 (1.41) 3.10 0.01
 Anxiety† 2.66 (1.35) 1.98 0.12 15.25 (1.29) 11.81 <0.001 2.73 (1.16) 2.35 0.04
 Fatigue 4.61 (1.61) 2.86 0.03 14.47 (1.67) 8.67 <0.001 4.31 (1.50) 2.87 0.02
 Empathy 0.30 (1.24) 0.24 0.83 −20.84 (1.45) −14.38 <0.001 −1.35 (1.30) −1.04 0.35
 Happy −0.64 (1.23) −0.52 0.83 −11.88 (1.36) −8.75 <0.001 0.10 (1.22) 0.08 0.93
 Sad −0.30 (1.42) −0.21 0.83 1.47 (1.81) 0.82 0.42 3.07 (1.63) 1.89 0.10
 Engaged 0.76 (1.32) 0.58 0.83 −14.98 (1.41) −10.59 <0.001 −2.28 (1.27) −1.79 0.10
B. Assessments of Patients and Clinical Cases
Patient Assessments
 Pain exaggeration† −0.02 (0.09) −0.18 0.86 1.22 (0.14) 8.70 <0.001 0.10 (0.13) 0.78 0.61
 Good historian† −0.23 (0.96) −0.24 0.86 −14.11 (1.33) −10.61 <0.001 −3.18 (1.20) −2.66 0.03
 Seriousness of patient condition 1.64 (1.01) 1.62 0.25 3.75 (1.75) 2.15 0.04 −2.90 (1.57) −1.85 0.15
 Patient cooperative 0.61 (0.92) 0.66 0.86 −34.31 (1.47) −23.38 <0.001 −1.53 (1.32) −1.16 0.43
 Patient engaged −0.31 (1.18) −0.26 0.86 −19.29 (1.65) −11.67 <0.001 −0.28 (1.49) −0.19 0.85
 Patient likeable −1.51 (0.85) −1.77 0.24 −36.79 (1.45) −25.39 <0.001 −4.50 (1.30) −3.46 <0.01
 Challenging case 4.03 (1.12) 3.59 <0.01 0.41 (1.71) 0.24 0.81 −0.69 (1.54) −0.45 0.77
Expected Patient Outcomes
 Treatment adherence −0.79 (1.03) −0.77 0.44 −17.48 (1.77) −9.88 <0.001 −4.93 (1.59) −3.10 <0.01
 Recovery from chief complaint 1.07 (0.88) 1.21 0.44 −1.41 (1.43) −0.99 0.32 −2.43 (1.28) −1.90 0.09
 Return to work 1.04 (1.32) 0.79 0.44 −7.80 (1.82) −4.28 <0.001 −0.95 (1.64) −0.58 0.56
C. Clinical Decisions, Behavior, and Diagnosis
Clinical Decisions and Behavior
 Patient priority level −0.03 (0.03) −1.07 0.54 −0.05 (0.06) −0.87 0.52 0.07 (0.05) 1.42 0.49
 Necessity of emergency care 1.55 (0.86) 1.82 0.54 −1.28 (1.38) −0.92 0.52 −1.65 (1.24) −1.33 0.49
 Total clinical tests ordered −0.08 (0.12) −0.70 0.65 0.24 (0.16) 1.45 0.52 −0.07 (0.15) −0.46 0.86
 Perceived knowledge of case −1.38 (1.03) −1.34 0.54 0.16 (1.97) 0.08 0.94 −0.29 (1.77) −0.16 0.87
 Likelihood of seeking consultation 1.33 (1.39) 0.96 0.54 4.95 (2.41) 2.05 0.32 −4.48 (2.17) −2.07 0.32
 Likelihood of admitting patient 1.78 (1.41) 1.26 0.54 3.15 (2.47) 1.28 0.52 −1.57 (2.22) −0.71 0.83
Diagnoses
OR z p OR z p OR z p
 Differential diagnosis 1.04 0.44 0.66 1.27 1.09 0.48 1.05 0.25 0.80
 Final diagnosis 1.12 1.19 0.31 1.44 1.93 0.21 0.88 −0.77 0.80
Coef.(SE) †† t p Coef.(SE) †† t p Coef. (SE) †† t p
 Confidence in final diagnosis −1.55 (1.06) −1.46 0.29 −0.08 (1.99) −0.04 0.97 1.02 (1.79) 0.57 0.80
†

Composite Measure (see Table 1 for details)

††

Unstandardized regression coefficients; Standardized coefficients (i.e., standardized effect sizes) are presented in the Supplement (Table S2)

Note. Coef = Coefficient; SE = Standard Error; OR = Odds Ratio. The coefficients for stress from uncertainty (SUS) and patient behavior repre-sent conditional effects. The coefficients for SUS refer to its effects averaged across both patient behavior conditions, and the coefficients for pa-tient behavior represent its effects at the mean level of SUS. All p-values are FDR-adjusted. Raw p-values are presented in the Supplement (Table S3)