TABLE 4.
Competition assays with complemented strains
Mutant straina | Median CIb | No. of micec | Pd | |
---|---|---|---|---|
Relevant genotype | Name | |||
Δ(Gifsy-2) pGP704 (vector) | JS232 | 0.014 | 12 | < 0.0005 |
Δ(Gifsy-2) psodCI+ | JS233 | 0.28 | 11 | < 0.0005 |
Δ(Gifsy-2) pgtgE+ | JS234 | 0.67 | 12 | NS |
Δ(Gifsy-2) pgtgE+sodCI+ | JS235 | 0.62 | 12 | NS |
All strains competed against an isogenic wild-type strain (JS231).
CI was calculated according to the formula in Materials and Methods, with the mutant as strain A and the wild type as strain B.
All assays were performed i.p. using BALB/c mice.
Student's t test was used to compare output versus inoculum. NS, not significant.