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. Author manuscript; available in PMC: 2026 Sep 3.
Published in final edited form as: Nat Rev Mol Cell Biol. 2021 Sep 14;23(2):125–140. doi: 10.1038/s41580-021-00405-2

Figure 1.

Figure 1.

DSB repair pathways. Resection by CtIP, Mre11, Rad50 and Nbs1 impairs repair by Nonhomologous end joining (NHEJ) and is required for Theta mediated end joining (TMEJ), Single strand annealing (SSA), and homologous recombination (HR). Repair products for TMEJ favors deletions at microhomologies in flanking DNA (in red).