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. 2026 Aug 20;17:1897284. doi: 10.3389/fphar.2026.1897284

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Copyright © 2026 Yue, Alhaskawi, Ezzi and Zhou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Flowchart depicting a systematic review process with steps: identification from databases and other sources, screening by title and abstract, eligibility assessed via full-text review, and inclusion of studies. Exclusion criteria include non-English publications, abstracts without full text, protocols, editorials, duplicate reports, and unrelated studies. Included studies comprise clinical trials, systematic reviews, meta-analyses, mechanistically relevant preclinical studies, and other relevant reviews. Color-coded sections label each stage: identification, screening, eligibility, and included. — PRISMA-style flow diagram summarizing the identification, screening, eligibility assessment, and final inclusion of studies in the narrative synthesis.