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. 2026 Aug 20;17:1897284. doi: 10.3389/fphar.2026.1897284

FIGURE 4.

Infographic illustrating the mechanism of exosome biogenesis and function in osteoarthritis, showing a human figure with highlighted knee, labeled exosome pathways from mesenchymal stem cells and stages including endocytosis, sorting endosomes, multivesicular bodies, exocytosis, and molecular cargo transfer related to cartilage regeneration.

Biogenesis, maturation, secretion, and cellular uptake of exosomes, illustrating early and late endosomal formation, multivesicular body (MVB) development, plasma membrane fusion, and exosome-mediated delivery of molecular cargo. The figure also highlights MSC-derived exosome contribution to cartilage regeneration in osteoarthritis.