Table 2.
Baseline laboratory findings, workflow metrics, and initial imaging characteristics.
| Variable | Medical treatment group (n = 128) | EVT group (n = 90) | Absolute SMD | P value |
|---|---|---|---|---|
| Laboratory findings | ||||
| White blood cell count, × 109/L | 7.62 ± 2.11 | 7.48 ± 2.05 | 0.067 | 0.624 |
| Hemoglobin, g/L | 138.7 ± 16.2 | 137.3 ± 15.8 | 0.087 | 0.525 |
| Platelet count, × 109/L | 214.5 ± 58.4 | 221.8 ± 61.7 | 0.122 | 0.380 |
| International normalized ratio | 1.01 ± 0.11 | 1.00 ± 0.10 | 0.095 | 0.486 |
| Serum creatinine, μmol/L | 76.8 ± 18.9 | 79.2 ± 19.4 | 0.125 | 0.365 |
| Fasting blood glucose, mmol/L | 7.34 ± 2.26 | 7.61 ± 2.41 | 0.116 | 0.405 |
| Low-density lipoprotein cholesterol, mmol/L | 2.63 ± 0.81 | 2.58 ± 0.77 | 0.063 | 0.645 |
| Baseline workflow metrics | ||||
| Onset-to-admission time, h | 18.6 ± 11.7 | 8.2 ± 5.0 | 1.156 | < 0.001 |
| Admission-to-initial CTA time, h | 1.9 ± 0.8 | 1.5 ± 0.7 | 0.532 | < 0.001 |
| Onset-to-initial CTA time, h | 20.5 ± 11.8 | 9.7 ± 5.1 | 1.188 | < 0.001 |
| Admission-to-initial CTP time, h | 2.3 ± 0.9 | 1.8 ± 0.8 | 0.587 | < 0.001 |
| Onset-to-initial CTP time, h | 20.9 ± 11.9 | 9.9 ± 5.1 | 1.202 | < 0.001 |
| Onset-to-intravenous thrombolysis time, h | 3.52 ± 0.76 | 3.38 ± 0.69 | 0.193 | 0.490 |
| Initial imaging characteristics | ||||
| Lesion type, overall P value | — | — | — | 0.889 |
| Severe stenotic lesion, n (%) | 78 (60.9) | 54 (60.0) | 0.019 | — |
| Occlusive lesion, n (%) | 50 (39.1) | 36 (40.0) | 0.019 | — |
| Responsible-vessel location, overall P value | — | — | — | 0.813 |
| Intracranial internal carotid artery, n (%) | 28 (21.9) | 24 (26.7) | 0.112 | — |
| Middle cerebral artery M1 segment, n (%) | 54 (42.2) | 33 (36.7) | 0.113 | — |
| Basilar artery, n (%) | 26 (20.3) | 18 (20.0) | 0.008 | — |
| Intracranial vertebral artery, n (%) | 20 (15.6) | 15 (16.7) | 0.028 | — |
| Collateral grade, overall P value | — | — | — | 0.001 |
| Worse than the contralateral side, n (%) | 52 (40.6) | 18 (20.0) | 0.460 | — |
| Equal to the contralateral side, n (%) | 46 (35.9) | 34 (37.8) | 0.038 | — |
| Better than the contralateral side, n (%) | 30 (23.4) | 38 (42.2) | 0.408 | — |
| Ischemic core volume, mL | 8.4 ± 7.3 | 7.9 ± 6.8 | 0.071 | 0.605 |
| Hypoperfusion volume, Tmax >6 s, mL | 42.6 ± 24.8 | 49.8 ± 27.5 | 0.275 | 0.049 |
| Mismatch volume, mL | 34.2 ± 22.7 | 41.9 ± 25.6 | 0.318 | 0.020 |
| Mismatch ratio | 3.1 ± 1.2 | 4.0 ± 1.5 | 0.663 | < 0.001 |
| Target ischemic penumbra on initial CTP, n (%) | 79 (61.7) | 78 (86.7) | 0.595 | < 0.001 |
CTA, computed tomography angiography; CTP, computed tomography perfusion; EVT, endovascular treatment; SMD, standardized mean difference; Tmax, time to maximum of the residue function.