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. 2026 Aug 7;18(8):e114149. doi: 10.7759/cureus.114149

Table 5. GIRISH quick-reference summary.

GA: Gestational age; GIRISH: Goal, Input, Role, Iterative refinement, Safety verification, and Human accountability; LLM: Large language model; MRN: Medical record number.

Step What you do Non-negotiable safety check
G – Goal One bounded task per interaction – one specific, answerable question. Vague goals return unverifiable answers.
I – Input Structured clinical context, fully anonymized. State what is unavailable. Never enter name, date of birth, or MRN into any LLM.
R – Role Tell the AI its role and limits (“do not prescribe; flag uncertainty and evidence grade”). Explicitly limiting scope reduces hallucination risk.
I – Iterate Interrogate the output. Challenge it. Ask what it is uncertain about. If the AI contradicts your gestalt, ask it to cite its source. Disagreement is information.
S – Safety Every drug dose and guideline – verify against your formulary before acting. Red flags: dose outside the GA range; a non-existent source; internal inconsistency; overconfident language.
H – Human A named clinician made the decision. Document it. “AI-assisted [task], GIRISH, [date]. Verified against [source]. Decision by [Name], [Designation].” The AI has no accountability; you do.