Table 2.
Drug use
|
No of subjects
|
No (%) of subjects developing schizophrenia
|
Odds ratio (95% CI)
|
|
---|---|---|---|---|
Crude
|
Adjusted*
|
|||
Cannabis ever† | 5391 | 73 (1.4) | 2.2 (1.7 to 2.8) | 1.5 (1.1 to 2.0) |
Frequency of use of cannabis (ever): | ||||
None | 36 429 | 215 (0.6) | 1.0† | 1.0† |
Once | 608 | 2 (0.3) | 0.6 (0.1 to 2.2) | 0.6 (0.1 to 2.3) |
2-4 times | 1380 | 8 (0.6) | 1.0 (0.5 to 2.0) | 0.9 (0.4 to 1.9) |
5-10 times | 806 | 9 (1.1) | 1.9 (1.0 to 3.7) | 1.4 (0.7 to 2.8) |
11-50 times | 689 | 13 (1.9) | 3.2 (1.8 to 5.7) | 2.2 (1.2 to 4.0) |
>50 times | 731 | 28 (3.8) | 6.7 (4.5 to 10.0) | 3.1 (1.7 to 5.5) |
Linear trend for frequency of use | — | — | 1.4 (1.3 to 1.5) | 1.2 (1.1 to 1.4) |
Adjusted for diagnosis at conscription to IQ score to poor social integration to disturbed behaviour to cigarette smoking to and place of upbringing.
No drug use as baseline comparison.