Fig. 4. Transcriptomic characterization of cellular responses to BT-Cl NPs + US treatment. (a) Heatmap of differentially expressed genes (DEGs) in the BT-Cl NPs + US and PBS groups. (b) Venn diagram showing the overlap of expressed genes between the two groups. (c) Volcano plot of DEGs between the two groups. Red and blue dots represent significantly upregulated and downregulated genes, respectively (|log2 FC| ≥ 1; padj ≤ 0.05). (d) GO enrichment analysis of DEGs. (e) KEGG pathway enrichment analysis of DEGs.
