Table 1. Patient's abnormal HIV labs (including HIV viral load, CD4 absolute count, and CD4%) across multiple encounters.
This patient presented during her first pregnancy at age 16 with abnormal HIV labs, including a high HIV viral load, low CD4 count, and low CD4%. A normal HIV viral load is considered "not detected", while a viral load of over 1,000 copies/mL is unsuppressed and >100,000 is very high. A CD4 count above 490 cells/mm3 and a CD4% above 30% are normal, while a CD4 count below 200 cells/mm3 and a CD4% less than 14% are diagnostic of AIDS. Though initiated on ART at this time, she continued to lack consistent treatment. When she re-presented during her second pregnancy at age 20, her CD4 count and CD4% had both decreased. She was repeatedly lost to follow-up. By age 26, her viral load had continued to rise while her CD4 count and CD4% had decreased, and she was officially diagnosed with AIDS. During her last hospital stay, shortly before being discharged to hospice, her viral load exceeded 3.7 million copies/mL while her CD4 count dropped to a mere 11 cells/mm3. The patient never achieved an undetectable HIV viral load nor a normal CD4 count.
Reference ranges were derived from the authors' institution.
HIV: human immunodeficiency virus; ART: antiretroviral therapy; AIDS: acquired immunodeficiency syndrome; /mL: per milliliter of blood; /mm3: per cubic millimeter of blood
| Patient value (age 16) | Patient value (age 20) | Patient value (age 26) | Patient value (age 27) | Reference range | |
| HIV viral load (copies/mL) | 38,300 | 15,700 | 48,300 | 3,720,000 | Not detected: normal; >1,000: unsuppressed; >100,000: very high |
| CD4 absolute count (cells/mm3) | 236 | 222 | <20 | 11 | 490-1,740: normal; <200: AIDS (severely immunocompromised) |
| CD4% | 21.0 | 17.0 | 7.0 | 10.6 | 30.0-61.0: normal; <14.0: AIDS (severely immunocompromised) |