Table 2.
Multivariable logistic regression assessing predictors of clinician confidence across four CPS-related domains.
| Genetic work-up (i) | Utilising somatic genetic information (ii) | Utilising germline genetic information (iii) | Counselling Families (iv) | |||||
|---|---|---|---|---|---|---|---|---|
| Predictor | OR (95%-CI) | p | OR (95%-CI) | p | OR (95%-CI) | p | OR (95%-CI) | p |
| Sex (female) | 1.42 (0.72–2.83) | 0.31 | 1.57 (0.84–2.95) | 0.16 | 1.33 (0.71–2.49) | 0.38 | 0.79 (0.4–1.51) | 0.47 |
| ≥10 years of experience | 1.51 (0.78–2.94) | 0.22 | 1.11 (0.6–2.05) | 0.74 | 0.67 (0.36–1.24) | 0.2 | 1.17 (0.61–2.25) | 0.63 |
| Access to a paediatric geneticist | 2.99 (1.35–6.89) | 0.0080* | 2.53 (1.17–5.78) | 0.022* | 1.85 (0.85–4.24) | 0.13 | 1.6 (0.71–3.84) | 0.27 |
| Access to a dedicated CPS clinic | 2.78 (1.42–5.53) | 0.0031* | 1.35 (0.72–2.56) | 0.35 | 1.37 (0.73–2.61) | 0.33 | 0.88 (0.45–1.72) | 0.71 |
CI confidence interval, CPS Cancer Predisposition Syndrome, OR odds ratio.